Thursday, November 11, 2010

Fine-scale East Eurasian admixture results (up to DOD179)

Following up on my analysis of North Eurasian population structure, I have decided to generate new admixture results for eligible project participants, to distinguish between different components of eastern origin that showed up as "East Asian" or "Northeast Asian" in the K=10 analysis. Eligible project members were:
  • Those that had some East Asian or Northeast Asian admixture, but lacked, to a large extent South Asian or East/West African admixture. This step was taken to ensure that the inferred components would be reserved for the West Eurasian and Siberian/Central/East Asian groups. In the future, there may be additional tests for South Asian-admixed individuals.
  • In case of relatives, whoever had the highest combined East Asian+Northeast Asian score
  • Only participants up to DOD179 were included. More recent IDs will be included in a separate run, once data submission in the Project is resumed.
Below is an ADMIXTURE K=7 barplot of the analysis, showing the 7 inferred components. Admixture proportions for this can be found in the spreadsheet.

Population portraits of individual-level variation can be found in this RAR. For example, the portrait of Nganasans...
... reveals the presence of a few individuals who deviate from the light blue "Nganasan" component.

To understand the relationship between the 7 components, here is a table of Fst distances between them:

The emergence of a Central Siberian component, highest in Selkup and Ket is very interesting; this may correspond to the postulated Proto-Uralic type that was detected by craniometric analysis by Moyseyev, as it is equidistant from East Asians and Caucasoids (about Fst=0.1).

Below are individual bars for project participants:
Individual admixture proportions can be found in the spreadsheet.

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